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Zimmer’s Puros DBM Putty is an all-natural moldable allograft. Even its carrier is 100% derived from allograft bone. This pre-mixed, ready-to-use moldable putty formulation provides excellent handling and time-savings. The pliable DBM putty, which holds its shape and does not flow when it is in a fluid environment, is easy to extrude from the open-bore dispenser. Using low-temperature, low-dose gamma radiation, Puros DBM is sterilized to SAL 10–6. After sterilization is complete, every donor lot of DBM is tested for osteoinductive potential in an in vivo ectopic rat assay. Only those DBM lots that show bone formation and have no significant inflammatory response are used for processing. Zimmer Dental adheres to strict quality control standards when processing DBM. Each lot comes from a single donor. In addition, the manufacturer meets or exceeds Food and Drug Administration and American Association of Tissue Banks donor screening and testing requirements.